The information on this website is not intended for diagnosis or treatment. Please consult your physician for health concerns.

+90 850 321 50 00

LMNA Cardiomyopathy

A genetic cardiomyopathy known as laminopathy, characterized by ventricular arrhythmia and early heart failure.

Written by: Saygı Hospital Health Guide Editorial Board
Published:

This content is for general information; please consult your physician for diagnosis and treatment.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Kardiyoloji department. Book Appointment →

What is LMNA Cardiomyopathy?

LMNA cardiomyopathy is the cardiac phenotype of the laminopathy spectrum caused by LMNA gene mutations. Cardiac involvement is also seen in Emery-Dreifuss muscular dystrophy and other laminopathies.

Characteristically, conduction disease appears first, followed by atrial arrhythmias, dilated cardiomyopathy and ventricular arrhythmias. The risk of sudden cardiac death is very high.

Early ICD implantation (with two or more risk factors) carries a class I recommendation. Heart transplantation may frequently be needed.

Symptoms

Palpitations
Syncope
Atrioventricular block
Heart failure
Muscle weakness
Contractures
Arrhythmia

Risk Factors

Family history
Positive LMNA mutation
History of Emery-Dreifuss
Atrial arrhythmia
Early conduction disease
Male sex (faster progression)
EF < 45%

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Unexplained AV block
  • Cardiomyopathy at a young age
  • Family history of sudden death
  • Muscle weakness with cardiac findings
  • Dilated cardiomyopathy with conduction disease
  • Positive LMNA mutation

Treatment Methods

01
Early ICD implantation
02
Heart failure therapy
03
Anticoagulation in AF
04
Ventricular arrhythmia control
05
Heart transplantation when needed
06
Family screening
07
Genetic counseling

Which Department to Visit?

You can visit our Kardiyoloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About Kardiyoloji Department

Let us help you

You can make an appointment with our specialists or contact us for your concerns.

Book AppointmentContact Us

Related Health Topics

Other articles from the same department you may want to explore.

Hypertension (High Blood Pressure)

Kardiyoloji

Hypertension is a condition in which blood pressure readings remain above 140/90 mmHg; early treatment helps prevent serious complications.

Coronary Artery Disease

Kardiyoloji

Narrowing of the coronary arteries due to atherosclerosis can cause chest pain (angina) and heart attack.

Heart Failure

Kardiyoloji

Heart failure is a chronic cardiac condition characterized by shortness of breath, leg swelling, and fatigue.

Heart Attack (Myocardial Infarction)

Kardiyoloji

A heart attack is a medical emergency; because heart muscle is lost by the minute, immediate intervention saves lives.

Atrial Fibrillation

Kardiyoloji

Atrial fibrillation is a common arrhythmia characterized by an irregular heartbeat and increased risk of stroke.

Heart Palpitations

Kardiyoloji

Palpitations are usually due to benign causes, but underlying cardiac rhythm disorders must be ruled out.

Heart Valve Diseases

Kardiyoloji

Valve stenosis or regurgitation increases the workload of the heart and, over time, can lead to heart failure.

Aortic Aneurysm

Kardiyoloji

Aortic aneurysms are often silent; early diagnosis allows treatment before rupture (a life-threatening tear).

Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.