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Dressler Syndrome

An immune-mediated pericarditis that develops weeks after myocardial infarction.

Written by: Saygı Hospital Health Guide Editorial Board
Published:

This content is for general information; please consult your physician for diagnosis and treatment.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Kardiyoloji department. Book Appointment →

What is Dressler Syndrome?

Dressler syndrome is an immune-mediated pericarditis that develops 2 to 10 weeks after myocardial infarction, cardiac surgery or cardiac trauma. Antibodies formed against damaged myocyte antigens trigger pericardial inflammation.

Typical findings include fever, pleuritic chest pain, pericardial and pleural effusions. Its incidence has declined with widespread reperfusion therapy, but it remains a recognized late complication of MI.

Diagnosis is based on clinical assessment, laboratory findings (elevated CRP and ESR) and imaging. NSAIDs and colchicine are first-line treatment; corticosteroids may be used in refractory cases.

Symptoms

Chest pain appearing 2–10 weeks after MI
Pleuritic character pain
Fever and malaise
Pericardial friction rub
Pleural effusion
Leukocytosis and elevated acute-phase reactants
Rarely cardiac tamponade

Risk Factors

Prior myocardial infarction
Cardiac surgery
Pericardiotomy
Cardiac trauma
Younger age
Pre-existing pericardial disease
Autoimmune predisposition

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • New chest pain weeks after MI
  • Fever accompanied by pleuritic pain
  • Dyspnea and signs of heart failure
  • Tamponade findings (hypotension, raised jugular venous pressure)

Treatment Methods

01
Non-steroidal anti-inflammatory drugs (high-dose aspirin or ibuprofen)
02
Colchicine (reduces recurrence)
03
Corticosteroids in refractory cases
04
Pericardiocentesis for tamponade
05
Echocardiographic follow-up
06
Reassessment of anticoagulation when appropriate

Which Department to Visit?

You can visit our Kardiyoloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.