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Coronary Microvascular Disease

Microvascular dysfunction causing angina with normal epicardial coronary arteries.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Kardiyoloji department. Book Appointment →

What is Coronary Microvascular Disease?

Coronary microvascular disease (CMVD) involves patients with angiographically normal epicardial coronary arteries but dysfunction in the coronary microvessels. It is an important component of the INOCA (Ischemia, Non-Obstructive Coronary Arteries) concept.

It is more common in women. Coronary flow reserve (CFR) and index of microcirculatory resistance (IMR) measurements are used in diagnosis. Major adverse cardiac event risk is increased compared with the normal population.

Symptoms

Typical angina (chest pain on exertion)
Normal coronary angiography
Ischemic findings on stress testing
Dyspnea
Resting angina (vasospastic component)

Risk Factors

Female sex
Hypertension
Diabetes mellitus
Obesity
Smoking
Systemic inflammatory diseases

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • When typical angina is present despite normal coronary angiography
  • Ischemia on stress testing with normal epicardial arteries
  • Treatment-resistant chest pain

Treatment Methods

01
Beta-blocker (first-line — heart rate control)
02
Calcium channel blockers (in vasospastic component)
03
Ranolazine (added for refractory angina)
04
Statin therapy (improves endothelial function)
05
ACE inhibitor (microvascular function support)
06
Lifestyle changes (exercise, weight control, smoking cessation)

Which Department to Visit?

You can visit our Kardiyoloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.