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Alcohol Septal Ablation in Hypertrophic Cardiomyopathy

A percutaneous therapy for obstructive HCM that reduces the interventricular septum with targeted alcohol injection.

Written by: Saygı Hospital Health Guide Editorial Board
Published:

This content is for general information; please consult your physician for diagnosis and treatment.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Kardiyoloji department. Book Appointment →

What is Alcohol Septal Ablation in Hypertrophic Cardiomyopathy?

Two main invasive options exist for obstructive hypertrophic cardiomyopathy (HCM) with persistent dyspnea, angina or syncope despite optimal medical therapy: surgical septal myectomy and alcohol septal ablation (ASA). ASA is a percutaneous alternative in selected patients.

During the procedure a catheter is advanced into a septal branch of the LAD and a small controlled amount of dehydrated alcohol is injected to create a controlled myocardial infarct in the target septum. Over time, fibrosis and retraction thin the septum and reduce left ventricular outflow tract obstruction.

ASA has a class IIa indication in older patients, those at high surgical risk, or those unsuitable for surgery with symptomatic obstructive HCM.

Symptoms

Exertional dyspnea
Chest pain
Syncope and presyncope
Palpitations
History of sudden cardiac death
Fatigue
Orthopnea

Risk Factors

Confirmed obstructive HCM
Family history
Genetic variants increasing sudden death risk
Unresponsiveness to medical therapy
High surgical risk
NYHA class III–IV symptoms
LVOT gradient ≥ 50 mmHg

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Refractory dyspnea and chest pain
  • Reduced exercise capacity
  • Syncope
  • Family history of sudden cardiac death
  • Symptoms uncontrolled by medication
  • New arrhythmias

Treatment Methods

01
Optimal beta-blocker or CCB therapy
02
Disopyramide
03
Alcohol septal ablation
04
Surgical myectomy as an alternative
05
ICD in high-risk patients
06
Arrhythmia management
07
Family screening program

Which Department to Visit?

You can visit our Kardiyoloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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Let us help you

You can make an appointment with our specialists or contact us for your concerns.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.