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Meconium Aspiration Syndrome (MAS)

The infant's aspiration of meconium-stained amniotic fluid into the airways causes respiratory distress.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Çocuk Sağlığı ve Hastalıkları department. Book Appointment →

What is Meconium Aspiration Syndrome (MAS)?

Meconium aspiration syndrome (MAS) develops when the baby passes meconium (the first stool) into the amniotic fluid during fetal distress and aspirates it during birth. Meconium-stained amniotic fluid is seen in 10-15% of term babies; MAS develops in 5-10% of these.

Meconium mechanically obstructs small airways, causing atelectasis, hyperinflation, and ventilation-perfusion mismatch. Chemical pneumonitis and surfactant inactivation also occur.

In severe cases, persistent pulmonary hypertension (PPHN), right-to-left shunt, and hypoxemia develop. Treatment includes respiratory support, surfactant, NO inhalation, and ECMO if needed.

Symptoms

Meconium-stained (green-black) amniotic fluid at birth
Cyanosis and low Apgar score at birth
Tachypnea and retractions
Expiratory grunting
Patchy infiltrates on chest radiograph
Persistent pulmonary hypertension

Risk Factors

Postmaturity (>41 weeks)
Fetal distress (IUGR, oligohydramnios)
Maternal hypertension and preeclampsia
Placental insufficiency
Cord prolapse
Prolonged labor

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • When meconium-stained amniotic fluid is present at birth
  • Signs of respiratory distress in the newborn
  • When cyanosis and apnea are observed
  • When neonatal intensive care is needed
  • Birth with low Apgar score

Treatment Methods

01
Appropriate resuscitation in the delivery room (routine intubation no longer recommended)
02
Oxygen therapy and CPAP
03
Mechanical ventilation (when needed)
04
Surfactant replacement (severe cases)
05
Inhaled nitric oxide (PPHN)
06
ECMO (in the most severe cases)

Which Department to Visit?

You can visit our Çocuk Sağlığı ve Hastalıkları department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About Çocuk Sağlığı ve Hastalıkları Department

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.